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#epigenetics

5 posts5 participants0 posts today
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ISOGG

“A stool sample, he explains, would contain DNA from colon tissue to help medical providers see evidence of mutations—the more mutations, the higher someone’s risk of colorectal cancer. Once you know someone is at high risk, you can take greater steps to monitor and catch the cancer early.” #dna #epigenetics #isogg #coloncancer #ecoli #colorectalcancer
news.yahoo.com/childhood-expos

Yahoo News · Childhood exposure to this bacteria could be driving rates of colorectal cancer in millennials and Gen Xers, new study warnsBy Ani Freedman
Continued thread
Public
Karl Theodor

„Wir müssen über #Cannabis diskutieren und dafür möchte ich die #Million einsetzen. Die #Politik muss sich endlich dieser #Debatte stellen.

hanfverband.de/millionaerswahl

#EndFossilFuels #EndFossilGas
#Traumata #fridaysforfuture #lastgeneration #climatecrisis #klimakatastrophe
#Epigenetics
#Endocannabinoide #Cannabinoide
#Kipppunkte #biohazard #hanf #hemp #climate

“The beginning of knowledge is the discovery of something we do not understand.”
― Frank Herbert #Zeitdilatation

26.01.2014 | Pressemitteilung | Georg Wurth Millionärswahl: Hanfverband gewinnt Million für die Legalisierung! Pressemitteilung des Deutschen Hanf Verbandes (DHV) Mit dem Sieg von Georg Wurth bei der Millionärswahl von Pro7 und Sat.1 am vergangenen Samstag feiert der Deutsche Hanf Verband einen seiner bisher größten Erfolge. Mit dem Gewinn wird der DHV die Debatte um einen sinnvolleren Umgang mit Cannabis in Deutschland vorantreiben. Georg Wurth erklärt hierzu: „Wir müssen über Cannabis diskutieren und dafür möchte ich die Million einsetzen. Die Politik muss sich endlich dieser Debatte stellen. In Colorado wird inzwischen völlig legal Cannabis verkauft, der US-Bundesstaat Washington und Uruguay als erste Nation sind gerade dabei, die entsprechenden Beschlüsse umzusetzen. Dies zeigt, dass eine andere Cannabispolitik möglich ist! Es geht nicht um eine Verharmlosung von Cannabis, sondern um eine Alternative zum Verbot. Die Cannabisprohibition ist gescheitert, schädlich und teuer – wir möchten den bestehenden Schwarzmarkt durch einen regulierten Markt mit Jugend- und Verbraucherschutz ersetzen.
Public
ISOGG

“So what has to happen is that methyltransferase has to hit that site over and over and over again, and it gradually builds up methylation … and only with repeated hits from the methyltransferase do we build up enough methylation that the gene actually gets silenced.” #DNA #isogg #Epigenetics #methylation #geneadons
chemistryworld.com/news/epigen

Cellular DNA and epigenetics
Chemistry WorldEpigenetic editors enter clinical trialsNew wave of precision medicines amplify or silence genes, without altering genetic code
Public
ISOGG

When someone has a mutated version of both copies of their MAL genes, they end up with an AnWj-negative blood type, like the pregnant patient. Tilley and team identified three patients with the rare blood type that didn't have this mutation, suggesting that sometimes blood disorders can also cause the antigen to be suppressed. #bloodgroup #MAL #epigenetics #isogg #geneadons sciencealert.com/researchers-i

ScienceAlert · Researchers Identify New Blood Group After 50 Year MysteryWhen a pregnant woman had her blood sampled back in 1972, doctors discovered it was mysteriously missing a surface molecule found on all other known red blood cells at the time.
Public
ISOGG

“The primary goal was to investigate the genotoxicity of 32 commonly consumed food additives and six mixtures corresponding to dietary exposure in France. While our findings indicate the potential toxicity of some combinations, further research is needed to determine whether the in vitro concentrations used are predictive of a possible human health risks.” #DNA #ISOGG #epigenetics #foodadditives #geneadons
sciencedirect.com/science/arti

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ma𝕏pool

3rd method if inheritance besides DNA and RNA: Amyloid-like protein structures that have the ability to replicate making them possible inheritance vectors.

Noncanonical inheritance of phenotypic information by protein amyloids nature.com/articles/s41556-024

>we identify amyloid-like protein structures that are stably inherited in wild-type animals and influence traits. Their perturbation by genetic, environmental or pharmacological treatments leads to developmental phenotypes that can be epigenetically passed onto progeny.

NatureNoncanonical inheritance of phenotypic information by protein amyloids - Nature Cell BiologyEroglu et al. describe protein amyloid structures that are stably inherited across generations and transmit epigenetic memory in Caenorhabditis elegans. MSTR protein loss results in a transgenerational feminization phenotype through ectopic GLD-1 expression.
#biology#cellbiology#epigenetics
Public
Moritz Bartl

"There is a growing understanding that mental illness has a crucial physical component and may cause disturbances of mind and body which strongly emphasizes a crucial role of psychotherapy focused on early stressful experiences mainly during critical developmental periods including prenatal and perinatal traumas."

"#epigenetics […] will likely be one of the most important areas of scientific research."

Janov, A. Epigenetics and Primal Therapy. Act Nerv Super 57, (2015). doi.org/10.1007/BF03379941

SpringerLinkEpigenetics and Primal Therapy - Activitas Nervosa SuperiorEpigenetics is focused on the study of how experience changes an individual’s genetic expression, previously considered inalterable. Recent pioneering research indicates that epigenetics is revolutionizing the study of mental health and challenging the belief that DNA is destiny. Moreover, in terms of the history of science, the new developments augur the convergence of previously distinct fields, psychology and biology. There is a growing understanding that mental illness has a crucial physical component and may cause disturbances of mind and body which strongly emphasis a crucial role of psychotherapy focused on early stressful experiences mainly during critical developmental periods including prenatal and perinatal traumas.
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